Publications from the ACE Study.
Below are listed the most important publications resulting from the ACE study. We have provided links to the abstract for each article and explainers for the most important cases. Our practice is underpinned by evidence and we are committed to rigourous scientific enquiry into all types of endoscopic resection.
Click on the links below to be taken to the article in question on PubMed. Use the buttons to filter the articles
Abbreviations; SSP - Sessile Serrated Polyp, DMI - Deep Mural Injury, SMIC - Submucosal invasive cancer, ICV - Ileocaecal Valve
| Type | Tag | Title | Authors | Journal |
|---|---|---|---|---|
| Original Article | SSP | The clinical significance and synchronous polyp burden of large (≥ 20 mm) sessile serrated polyps in patients without serrated polyposis syndrome. | Desomer L, Tate DJ, Jayanna M, Pellise M, Awadie H, Burgess NG, McLeod D, Mahajan H, Lee EYT, Williams SJ, Bourke MJ. | Endoscopy. 2018 |
| Original Article | EMR outcomes | The size, morphology, site, and access score predicts critical outcomes of endoscopic mucosal resection in the colon. | Sidhu M, Tate DJ, Desomer L, Brown G, Hourigan LF, Lee EYT, Moss A, Raftopoulos S, Singh R, Williams SJ, Zanati S, Burgess N, Bourke MJ. | Endoscopy. 2018 |
| Original Article | EMR of laterally spreading lesions around or involving the appendiceal orifice: technique, risk factors for failure, and outcomes of a tertiary referral cohort (with video). | Tate DJ, Desomer L, Awadie H, Goodrick K, Hourigan L, Singh R, Williams SJ, Bourke MJ. | Gastrointest Endosc. 2018 | |
| Original Article | SSP | Wide-field piecemeal cold snare polypectomy of large sessile serrated polyps without a submucosal injection is safe. | Tate DJ, Awadie H, Bahin FF, Desomer L, Lee R, Heitman SJ, Goodrick K, Bourke MJ. | Endoscopy. 2018 |
| Original Article | Avoiding Surgery | Cold-forceps avulsion with adjuvant snare-tip soft coagulation (CAST) is an effective and safe strategy for the management of non-lifting large laterally spreading colonic lesions. | Tate DJ, Bahin FF, Desomer L, Sidhu M, Gupta V, Bourke MJ. | Endoscopy. 2018 |
| Original Article | SSP | A standardized imaging protocol for the endoscopic prediction of dysplasia within sessile serrated polyps (with video). | Tate DJ, Jayanna M, Awadie H, Desomer L, Lee R, Heitman SJ, Sidhu M, Goodrick K, Burgess NG, Mahajan H, McLeod D, Bourke MJ. | Gastrointest Endosc. 2018 |
| Original Article | SMIC | Risk Stratification for Covert Invasive Cancer Among Patients Referred for Colonic Endoscopic Mucosal Resection: A Large Multi-center Cohort. | Burgess NG, Hourigan LF, Zanati SA, Brown GJ, Singh R, Williams SJ, Raftopoulos SC, Ormonde D, Moss A, Byth K, Mahajan H, McLeod D, Bourke MJ. | Gastroenterology. 2017 |
| Original Article | Avoiding surgery | Two-stage endoscopic mucosal resection is a safe and effective salvage therapy after a failed single-session approach. | Tate DJ, Desomer L, Hourigan LF, Moss A, Singh R, Bourke MJ. | Endoscopy. 2017 |
| Best Practice | SSP | Sessile Serrated Adenomas: How to Detect, Characterize and Resect. | Ma MX, Bourke MJ. | Gut Liver. 2017 |
| Best Practice | Management of colonic polyps: an advancing discipline. | Klein A, Bourke MJ. | ANZ J Surg. 2017 | |
| Best Practice | The colonoscopist's guide to the vocabulary of colorectal neoplasia: histology, morphology, and management. | Rex DK, Hassan C, Bourke MJ. | Gastrointest Endosc. 2017 | |
| Best Practice | Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. | Ferlitsch M, Moss A, Hassan C, Bhandari P, Dumonceau JM, Paspatis G, Jover R, Langner C, Bronzwaer M, Nalankilli K, Fockens P, Hazzan R, Gralnek IM, Gschwantler M, Waldmann E, Jeschek P, Penz D, Heresbach D, Moons L, Lemmers A, Paraskeva K, Pohl J, et al. | Endoscopy. 2017 | |
| Best Practice | Optimizing Resection of Large Colorectal Polyps. | Heitman SJ, Tate DJ, Bourke MJ. | Curr Treat Options Gastroenterol. 2017 | |
| Best Practice | How to Perform High-Quality Endoscopic Mucosal Resection During Colonoscopy. | Klein A, Bourke MJ. | Gastroenterology. 2017 | |
| Editorial | Endoscopic detection of large and advanced colonic lesions: Are we missing the forest for the trees? | Tate DJ, Burgess NG, Bourke MJ. | Gastrointest Endosc. 2017 | |
| Best Practice | Complications of endoscopic polypectomy, endoscopic mucosal resection and endoscopic submucosal dissection in the colon. | Ma MX, Bourke MJ. | Best Pract Res Clin Gastroenterol. 2016 | |
| Original Article | Recurrence | Adenoma recurrence after piecemeal colonic EMR is predictable: the Sydney EMR recurrence tool. | Tate DJ, Desomer L, Klein A, Brown G, Hourigan LF, Lee EY, Moss A, Ormonde D, Raftopoulos S, Singh R, Williams SJ, Zanati S, Byth K, Bourke MJ. | Gastrointest Endosc. 2017 |
| Best Practice | Mucosal colonic defect post EMR or ESD: to close or not? | Burgess NG, Bourke MJ. | Endosc Int Open. 2016 | |
| Original Article | Molecular | Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors. | Hesson LB, Ng B, Zarzour P, Srivastava S, Kwok CT, Packham D, Nunez AC, Beck D, Ryan R, Dower A, Ford CE, Pimanda JE, Sloane MA, Hawkins NJ, Bourke MJ, Wong JW, Ward RL. | Mol Cancer Res. 2016 |
| Original Article | DMI | Deep mural injury and perforation after colonic endoscopic mucosal resection: a new classification and analysis of risk factors. | Burgess NG, Bassan MS, McLeod D, Williams SJ, Byth K, Bourke MJ. | Gut. 2016 |
| Best Practice | EMR should be the first-line treatment for large laterally spreading colorectal lesions. | Lee EY, Bourke MJ. | Gastrointest Endosc. 2016 | |
| Original Article | Recurrence | A standardized imaging protocol is accurate in detecting recurrence after EMR. | Desomer L, Tutticci N, Tate DJ, Williams SJ, McLeod D, Bourke MJ. | Gastrointest Endosc. 2017 |
| Original Article | Post EMR Bleeding | Prediction of Clinically Significant Bleeding Following Wide-Field Endoscopic Resection of Large Sessile and Laterally Spreading Colorectal Lesions: A Clinical Risk Score. | Bahin FF, Rasouli KN, Byth K, Hourigan LF, Singh R, Brown GJ, Zanati SA, Moss A, Raftopoulos S, Williams SJ, Bourke MJ. | Am J Gastroenterol. 2016 |
| Original Article | Recurrence | Extended endoscopic mucosal resection does not reduce recurrence compared with standard endoscopic mucosal resection | Bahin FF, Pellise M, Williams SJ, Bourke MJ. | Gastrointest Endosc. 2016 |
| Best Practice | Endoscopic resection of subtotal or completely circumferential laterally spreading colonic adenomas: technique, caveats, and outcomes. | Tutticci N, Klein A, Sonson R, Bourke MJ. | Endoscopy. 2016 | |
| Original Article | SSP | Endoscopic mucosal resection for large serrated lesions in comparison with adenomas: a prospective multicentre study of 2000 lesions. | Pellise M, Burgess NG, Tutticci N, Hourigan LF, Zanati SA, Brown GJ, Singh R, Williams SJ, Raftopoulos SC, Ormonde D, Moss A, Byth K, P'Ng H, Mahajan H, McLeod D, Bourke MJ. | Gut. 2017 |
| Best Practice | Expanding the field of cold snare polypectomy. | Desomer L, Bourke MJ. | Endosc Int Open. 2015 | |
| Original Article | Recurrence | The influence of clips on scars after EMR: clip artifact. | Pellis | Gastrointest Endosc. 2016 |
| Original Article | EMR Cost vs Surgery | Cost Analysis of Endoscopic Mucosal Resection vs Surgery for Large Laterally Spreading Colorectal Lesions. | Jayanna M, Burgess NG, Singh R, Hourigan LF, Brown GJ, Zanati SA, Moss A, Lim J, Sonson R, Williams SJ, Bourke MJ. | Clin Gastroenterol Hepatol. 2016 |
| Best Practice | Endoscopic resection of colorectal lesions: The narrowing divide between East and West. | Burgess NG, Bourke MJ. | Dig Endosc. 2016 | |
| Original Article | Cold Snare | Characterization and significance of protrusions in the mucosal defect after cold snare polypectomy. | Tutticci N, Burgess NG, Pellise M, Mcleod D, Bourke MJ. | Gastrointest Endosc. 2015 |
| Best Practice | Advanced polypectomy and resection techniques. | Klein A, Bourke MJ. | Gastrointest Endosc Clin N Am. 2015 | |
| Best Practice | Colonic polypectomy (with videos). | Burgess NG, Bahin FF, Bourke MJ. | Gastrointest Endosc. 2015 | |
| Original Article | ICV LSL | Endoscopic mucosal resection of laterally spreading lesions involving the ileocecal valve: technique, risk factors for failure, and outcomes. | Nanda KS, Tutticci N, Burgess NG, Sonson R, Williams SJ, Bourke MJ. | Endoscopy. 2015 |
| Original Article | SSP Dysplasia | Clinical and endoscopic predictors of cytological dysplasia or cancer in a prospective multicentre study of large sessile serrated adenomas/polyps. | Burgess NG, Pellise M, Nanda KS, Hourigan LF, Zanati SA, Brown GJ, Singh R, Williams SJ, Raftopoulos SC, Ormonde D, Moss A, Byth K, P'Ng H, McLeod D, Bourke MJ. | Gut. 2016 |
| Original Article | Post EMR Bleeding | Prophylactic endoscopic coagulation to prevent bleeding after wide-field endoscopic mucosal resection of large sessile colon polyps. | Bahin FF, Naidoo M, Williams SJ, Hourigan LF, Ormonde DG, Raftopoulos SC, Holt BA, Sonson R, Bourke MJ. | Clin Gastroenterol Hepatol. 2015 |
| Best Practice | Colorectal endoscopic submucosal dissection: when and by whom? | Bourke MJ, Neuhaus H. | Endoscopy. 2014 | |
| Original Article | Injection technique | Intramucosal injection: part of the spectrum of outcomes from submucosal injection during endoscopic resection. | Nanda KS, Sonson RJ, Bourke MJ. | Gastrointest Endosc. 2014 |
| Original Article | Recurrence | Long-term adenoma recurrence following wide-field endoscopic mucosal resection (WF-EMR) for advanced colonic mucosal neoplasia is infrequent: results and risk factors in 1000 cases from the Australian Colonic EMR (ACE) study. | Moss A, Williams SJ, Hourigan LF, Brown G, Tam W, Singh R, Zanati S, Burgess NG, Sonson R, Byth K, Bourke MJ. | Gut. 2015 |
| Original Article | Circumferential LSL | Endoscopic resection of subtotal and complete circumferential colonic advanced mucosal neoplasia. | Tutticci N, Sonson R, Bourke MJ. | Gastrointest Endosc. 2014 |
| Original Article | Mortality of EMR vs Surgery | Actual endoscopic versus predicted surgical mortality for treatment of advanced mucosal neoplasia of the colon. | Ahlenstiel G, Hourigan LF, Brown G, Zanati S, Williams SJ, Singh R, Moss A, Sonson R, Bourke MJ; Australian Colonic Endoscopic Mucosal Resection (ACE) Study Group.. | Gastrointest Endosc. 2014 |
| Original Article | SSP Dysplasia | Sessile serrated adenomas/polyps with cytologic dysplasia: a triple threat for interval cancer. | Burgess NG, Tutticci NJ, Pellise M, Bourke MJ. | Gastrointest Endosc. 2014 |
| Original Article | SSP Dysplasia | Caught in the act: endoscopic characterization of sessile serrated adenomas with dysplasia. | Nanda KS, Tutticci N, Burgess N, Sonson R, McLeod D, Bourke MJ. | Gastrointest Endosc. 2014 |
| Original Article | Post EMR Bleeding | A management algorithm based on delayed bleeding after wide-field endoscopic mucosal resection of large colonic lesions. | Burgess NG, Williams SJ, Hourigan LF, Brown GJ, Zanati SA, Singh R, Tam W, Butt J, Byth K, Bourke MJ. | Clin Gastroenterol Hepatol. 2014 |
| Best Practice | Advanced endoscopic resection in the colon: recent innovations, current limitations and future directions. | Tutticci N, Bourke MJ. | Expert Rev Gastroenterol Hepatol. 2014 | |
| Original Article | Intraprocedural bleeding | Risk factors for intraprocedural and clinically significant delayed bleeding after wide-field endoscopic mucosal resection of large colonic lesions. | Burgess NG, Metz AJ, Williams SJ, Singh R, Tam W, Hourigan LF, Zanati SA, Brown GJ, Sonson R, Bourke MJ. | Clin Gastroenterol Hepatol. 2014 |
| Original Article | Anorectal LSL | Advanced mucosal neoplasia of the anorectal junction: endoscopic resection technique and outcomes (with videos). | Holt BA, Bassan MS, Sexton A, Williams SJ, Bourke MJ. | Gastrointest Endosc. 2014 |
| Original Article | Intraprocedural bleeding | Snare tip soft coagulation achieves effective and safe endoscopic hemostasis during wide-field endoscopic resection of large colonic lesions (with videos). | Fahrtash-Bahin F, Holt BA, Jayasekeran V, Williams SJ, Sonson R, Bourke MJ. | Gastrointest Endosc. 2013 |
| Original Article | Topic submucosal chromendoscopy | Topical submucosal chromoendoscopy defines the level of resection in colonic EMR and may improve procedural safety (with video). | Holt BA, Jayasekeran V, Sonson R, Bourke MJ. | Gastrointest Endosc. 2013 |
| Original Article | Molecular | A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations. | Metz AJ, Bourke MJ, Moss A, Dower A, Zarzour P, Hawkins NJ, Ward RL, Hesson LB. | Eur J Gastroenterol Hepatol. 2013 |
| Original Article | CO2 vs O2 | Carbon dioxide insufflation reduces number of postprocedure admissions after endoscopic resection of large colonic lesions: a prospective cohort study. | Bassan MS, Holt B, Moss A, Williams SJ, Sonson R, Bourke MJ. | Gastrointest Endosc. 2013 |
| Best Practice | Wide field endoscopic resection for advanced colonic mucosal neoplasia: current status and future directions. | Holt BA, Bourke MJ. | Clin Gastroenterol Hepatol. 2012 | |
| Best Practice | Endoscopic management of colonoscopic perforations. | Holt BA, Bassan MS, Bourke MJ. | Gastrointest Endosc. 2012 | |
| Best Practice | Endoscopic resection for mucosal neoplasia: pushing the boundaries, confronting the reality. | Bourke MJ. | J Gastroenterol Hepatol. 2011 | |
| Original Article | Post EMR Bleeding | Factors that predict bleeding following endoscopic mucosal resection of large colonic lesions. | Metz AJ, Bourke MJ, Moss A, Williams SJ, Swan MP, Byth K. | Endoscopy. 2011 |
| Original Article | Tattoo | Safety of colonic tattoo with sterile carbon particle suspension: a proposed guideline with illustrative cases. | Moss A, Bourke MJ, Pathmanathan N. | Gastrointest Endosc. 2011 |
| Original Article | EMR outcomes | Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. | Moss A, Bourke MJ, Williams SJ, Hourigan LF, Brown G, Tam W, Singh R, Zanati S, Chen RY, Byth K. | Gastroenterology. 2011 |
| Original Article | Target sign | The target sign: an endoscopic marker for the resection of the muscularis propria and potential perforation during colonic endoscopic mucosal resection. | Swan MP, Bourke MJ, Moss A, Williams SJ, Hopper A, Metz A. | Gastrointest Endosc. 2011 |
| Original Article | Injection solution | Succinylated gelatin substantially increases en bloc resection size in colonic EMR: a randomized, blinded trial in a porcine model. | Moss A, Bourke MJ, Kwan V, Tran K, Godfrey C, McKay G, Hopper AD. | Gastrointest Endosc. 2010 |
| Original Article | The suction pseudopolyp technique: a novel method for the removal of small flat nonpolypoid lesions of the colon and rectum. | Pattullo V, Bourke MJ, Tran KL, McLeod D, Williams SJ, Bailey AA, Alexander S, Mishra A, Co J. | Endoscopy. 2009 | |
| Original Article | Large refractory colonic polyps: is it time to change our practice? A prospective study of the clinical and economic impact of a tertiary referral colonic mucosal resection and polypectomy service (with videos). | Swan MP, Bourke MJ, Alexander S, Moss A, Williams SJ. | Gastrointest Endosc. 2009 |